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Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo

Mobilized peripheral blood cells (MPBCs) graft and peripheral blood cells apheresis are used for bone marrow transplantation and for treatment of graft versus host disease (GvHD). We demonstrate that a short treatment of MPBCs with Fas ligand (FasL, CD95L) for 2 h using a closed automated cell proce...

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Detalles Bibliográficos
Autores principales: Rodionov, Galina, Rosenzwaig, Michal, Tzadok, Michal Schrift, Kvint, Moran, Gevir, Elazar, Zorde-Khvalevsky, Elina, Peled, Amnon, Yarkoni, Shai, Ofer, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088133/
https://www.ncbi.nlm.nih.gov/pubmed/35538142
http://dx.doi.org/10.1038/s41409-022-01698-3