Structural basis of TRPV5 regulation by physiological and pathophysiological modulators

Transient receptor potential vanilloid 5 (TRPV5) is a kidney-specific Ca(2+)-selective ion channel that plays a key role in Ca(2+) homeostasis. The basal activity of TRPV5 is balanced through activation by phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and inhibition by Ca(2+)-bound calmodulin...

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Detalles Bibliográficos
Autores principales: Fluck, Edwin C., Yazici, Aysenur Torun, Rohacs, Tibor, Moiseenkova-Bell, Vera Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088182/
https://www.ncbi.nlm.nih.gov/pubmed/35476976
http://dx.doi.org/10.1016/j.celrep.2022.110737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088182/
https://www.ncbi.nlm.nih.gov/pubmed/35476976
http://dx.doi.org/10.1016/j.celrep.2022.110737

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