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Structural basis of TRPV5 regulation by physiological and pathophysiological modulators
Transient receptor potential vanilloid 5 (TRPV5) is a kidney-specific Ca(2+)-selective ion channel that plays a key role in Ca(2+) homeostasis. The basal activity of TRPV5 is balanced through activation by phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and inhibition by Ca(2+)-bound calmodulin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088182/ https://www.ncbi.nlm.nih.gov/pubmed/35476976 http://dx.doi.org/10.1016/j.celrep.2022.110737 |