PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells

OBJECTIVE: Glycogen synthase kinase-3β (GSK3β) has been recognized as a suppressor of Wnt/β-catenin signaling, which is critical for the stemness maintenance of breast cancer stem cells. However, the regulatory mechanisms of GSK3β protein expression remain elusive. METHODS: Co-immunoprecipitation an...

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Detalles Bibliográficos
Autores principales: Tang, Wei, Wu, Yu, Qi, Xin, Yu, Rilei, Lu, Zhimin, Chen, Ao, Fan, Xinglong, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088184/
https://www.ncbi.nlm.nih.gov/pubmed/34403222
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088184/
https://www.ncbi.nlm.nih.gov/pubmed/34403222
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0362

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