Cargando…
PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells
OBJECTIVE: Glycogen synthase kinase-3β (GSK3β) has been recognized as a suppressor of Wnt/β-catenin signaling, which is critical for the stemness maintenance of breast cancer stem cells. However, the regulatory mechanisms of GSK3β protein expression remain elusive. METHODS: Co-immunoprecipitation an...
Autores principales: | Tang, Wei, Wu, Yu, Qi, Xin, Yu, Rilei, Lu, Zhimin, Chen, Ao, Fan, Xinglong, Li, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088184/ https://www.ncbi.nlm.nih.gov/pubmed/34403222 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0362 |
Ejemplares similares
-
Hsp90 Maintains the Stability and Function of the Tau Phosphorylating Kinase GSK3β
por: Dou, Fei, et al.
Publicado: (2007) -
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β
por: Wang, Chongyang, et al.
Publicado: (2023) -
PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma
por: Zhou, Jing-Wei, et al.
Publicado: (2019) -
The Distinct Assignments for Hsp90α and Hsp90β: More Than Skin Deep
por: Chang, Cheng, et al.
Publicado: (2023) -
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6
por: Liao, Liping, et al.
Publicado: (2022)