Comparative thermodynamic analysis in solution of a next generation antibody mimetic to VEGF

An antibody mimetic known as Fab–PEG–Fab (FpF) is a stable bivalent molecule that may have some potential therapeutic advantages over IgG antibodies due to differences in their binding kinetics as determined by surface plasmon resonance. Here we describe the thermodynamic binding properties to vascu...

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Detalles Bibliográficos
Autores principales: Khalili, Hanieh, Brocchini, Steve, Khaw, Peng Tee, Filippov, Sergey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088213/
https://www.ncbi.nlm.nih.gov/pubmed/35547916
http://dx.doi.org/10.1039/c8ra07059h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088213/
https://www.ncbi.nlm.nih.gov/pubmed/35547916
http://dx.doi.org/10.1039/c8ra07059h

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