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Cyclic Thiosulfonates for Thiol-Mediated Uptake: Cascade Exchangers, Transporters, Inhibitors

[Image: see text] Thiol-mediated uptake is emerging as a powerful method to penetrate cells. Cyclic oligochalcogenides (COCs) have been identified as privileged scaffolds to enable and inhibit thiol-mediated uptake because they can act as dynamic covalent cascade exchangers, i.e., every exchange pro...

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Detalles Bibliográficos
Autores principales: Kato, Takehiro, Lim, Bumhee, Cheng, Yangyang, Pham, Anh-Tuan, Maynard, John, Moreau, Dimitri, Poblador-Bahamonde, Amalia I., Sakai, Naomi, Matile, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088311/
https://www.ncbi.nlm.nih.gov/pubmed/35557769
http://dx.doi.org/10.1021/jacsau.1c00573