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Identification of a novel ene reductase from Pichia angusta with potential application in (R)-levodione production

Asymmetric reduction of electronically activated alkenes by ene reductases (ERs) is an attractive approach for the production of enantiopure chiral products. Herein, a novel FMN-binding ene reductase (PaER) from Pichia angusta was heterologously expressed in Escherichia coli BL21(DE3), and the recom...

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Detalles Bibliográficos
Autores principales: Zhang, Baoqi, Sun, Jiale, Zheng, Yanqiu, Mao, Xinlei, Lin, Jinping, Wei, Dongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088392/
https://www.ncbi.nlm.nih.gov/pubmed/35558851
http://dx.doi.org/10.1039/d2ra01716d