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One-step preparation of novel 1-(N-indolyl)-1,3-butadienes by base-catalysed isomerization of alkynes as an access to 5-(N-indolyl)-naphthoquinones

A series of novel 1-(N-indolyl)-1,3-butadienes, as (1 : 1) mixtures of the (E) and (Z) dienes, was prepared in one step by base-catalysed isomerization of N-alkylindoles with a terminal butyne chain. The reaction conditions are mild, and in all cases the yields were very high (>90%). The (E) and...

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Detalles Bibliográficos
Autores principales: Pis Diez, C. M., Fernandez, J. F., Di Venosa, G., Casas, A., Pis Diez, R., Palermo, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088550/
https://www.ncbi.nlm.nih.gov/pubmed/35558441
http://dx.doi.org/10.1039/c8ra05208e