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An Approach to Derive Functional Peptide Inhibitors of Transcription Factor Activity
[Image: see text] We report the development of a high-throughput, intracellular “transcription block survival” (TBS) screening platform to derive functional transcription factor antagonists. TBS is demonstrated using the oncogenic transcriptional regulator cJun, with the development of antagonists t...
Autores principales: | Brennan, Andrew, Leech, James T., Kad, Neil M., Mason, Jody M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088798/ https://www.ncbi.nlm.nih.gov/pubmed/35557753 http://dx.doi.org/10.1021/jacsau.2c00105 |
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