Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression

Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration due to dystrophin gene mutations. Patients with DMD initially experience muscle weakness in their limbs during adolescence. With age, patients develop fatal respiratory and cardiac dysfunctions....

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Detalles Bibliográficos
Autores principales: Song, Min Ho, Yoo, Jimeen, Oh, Jae Gyun, Kook, Hyun, Park, Woo Jin, Jeong, Dongtak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088811/
https://www.ncbi.nlm.nih.gov/pubmed/35557546
http://dx.doi.org/10.3389/fcvm.2022.763544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088811/
https://www.ncbi.nlm.nih.gov/pubmed/35557546
http://dx.doi.org/10.3389/fcvm.2022.763544

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