Identifying New Ligands for JNK3 by Fluorescence Thermal Shift Assays and Native Mass Spectrometry

[Image: see text] The c-Jun N-terminal kinases (JNKs) are evolutionary highly conserved serine/threonine kinases. Numerous findings suggest that JNK3 is involved in the pathogenesis of neurodegenerative diseases, so the inhibition of JNK3 may be a potential therapeutic intervention. The identificati...

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Detalles Bibliográficos
Autores principales: Cheng, Chongyun, Liu, Miaomiao, Gao, Xiaoqin, Wu, Dong, Pu, Mengchen, Ma, Jun, Quinn, Ronald J., Xiao, Zhicheng, Liu, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088906/
https://www.ncbi.nlm.nih.gov/pubmed/35559183
http://dx.doi.org/10.1021/acsomega.2c00340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088906/
https://www.ncbi.nlm.nih.gov/pubmed/35559183
http://dx.doi.org/10.1021/acsomega.2c00340

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