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Dissecting Intra-Tumoral Changes Following Immune Checkpoint Blockades in Intrahepatic Cholangiocarcinoma via Single-Cell Analysis

PURPOSE: To dissect the tumor ecosystem following immune checkpoint blockades (ICBs) in intrahepatic cholangiocarcinoma (ICC) at a single-cell level. METHODS: Single-cell RNA sequencing (scRNA-seq) data of 10 ICC patients for the ICB clinical trial were extracted from GSE125449 and systematically re...

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Detalles Bibliográficos
Autores principales: Sun, Bao-Ye, Zhou, Cheng, Guan, Ruo-Yu, Liu, Gao, Yang, Zhang-Fu, Wang, Zhu-Tao, Gan, Wei, Zhou, Jian, Fan, Jia, Yi, Yong, Qiu, Shuang-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088915/
https://www.ncbi.nlm.nih.gov/pubmed/35558087
http://dx.doi.org/10.3389/fimmu.2022.871769