Exploring the binding pattern between pepsin and deferasirox using detailed experimental and computer simulation methods

Steady-state fluorescence spectroscopy indicated that a ground state complex was formed between deferasirox (DFX) and pepsin. The binding parameters and thermodynamic parameters of pepsin–DFX complex formation suggested the presence of only one high affinity binding site in the binding process of DF...

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Detalles Bibliográficos
Autores principales: Yang, Ji, Du, Qiaohong, Gan, Na, Chen, Yongkuan, Yang, Liu, Liu, Zhihua, Zhao, Hui, Sun, Qiaomei, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088941/
https://www.ncbi.nlm.nih.gov/pubmed/35557832
http://dx.doi.org/10.1039/c8ra07993e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088941/
https://www.ncbi.nlm.nih.gov/pubmed/35557832
http://dx.doi.org/10.1039/c8ra07993e

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