Cargando…
Exploring the binding pattern between pepsin and deferasirox using detailed experimental and computer simulation methods
Steady-state fluorescence spectroscopy indicated that a ground state complex was formed between deferasirox (DFX) and pepsin. The binding parameters and thermodynamic parameters of pepsin–DFX complex formation suggested the presence of only one high affinity binding site in the binding process of DF...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088941/ https://www.ncbi.nlm.nih.gov/pubmed/35557832 http://dx.doi.org/10.1039/c8ra07993e |