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An improved HPLC-MS/MS method for simultaneous quantification of propranolol and its two phase I metabolites in plasma of infants with hemangioma and its application to a comparative study of plasma concentrations

Propranolol is now a preferred treatment for infantile hemangioma. However, there are no published papers on the metabolism and concentrations of propranolol in the plasma of infants with hemangioma. In the present study, a sensitive, simple and reliable method was developed and validated for the si...

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Detalles Bibliográficos
Autores principales: He, Huan, Li, Li, Zhao, Libo, Sun, Ning, Zhang, Meng, Cheng, Ying, Yu, Lu, Ma, Lin, Wang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089243/
https://www.ncbi.nlm.nih.gov/pubmed/35557780
http://dx.doi.org/10.1039/c8ra06252h