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SMC complexes: Lifting the lid on loop extrusion

Loop extrusion has emerged as a prominent hypothesis for how SMC complexes shape chromosomes – single molecule in vitro observations have yielded fascinating images of this process. When not extruding loops, SMC complexes are known to topologically entrap one or more DNAs. Here, we review how struct...

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Detalles Bibliográficos
Autores principales: Higashi, Torahiko L., Uhlmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089308/
https://www.ncbi.nlm.nih.gov/pubmed/35016058
http://dx.doi.org/10.1016/j.ceb.2021.12.003