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SMC complexes: Lifting the lid on loop extrusion
Loop extrusion has emerged as a prominent hypothesis for how SMC complexes shape chromosomes – single molecule in vitro observations have yielded fascinating images of this process. When not extruding loops, SMC complexes are known to topologically entrap one or more DNAs. Here, we review how struct...
Autores principales: | Higashi, Torahiko L., Uhlmann, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089308/ https://www.ncbi.nlm.nih.gov/pubmed/35016058 http://dx.doi.org/10.1016/j.ceb.2021.12.003 |
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