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pH-responsive and porous vancomycin-loaded PLGA microspheres: evidence of controlled and sustained release for localized inflammation inhibition in vitro

Adequate delivery of antibiotics to infected sites is crucial for the effective treatment of bacterial infections. A controlled and sustained release system based on porous and pH-responsive poly(lactic-co-glycolic acid) (PLGA)–vancomycin (Van) microspheres was developed. In this system, drug releas...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoling, Pan, Qingqing, Zheng, Zongfu, Chen, Yongzhong, Chen, Yuyuan, Weng, Shaohuang, Huang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089331/
https://www.ncbi.nlm.nih.gov/pubmed/35557787
http://dx.doi.org/10.1039/c8ra06659k