Palladium-Catalyzed α-Arylation of Cyclic β-Dicarbonyl Compounds for the Synthesis of Ca(V)1.3 Inhibitors

[Image: see text] Cyclic α-aryl β-dicarbonyl derivatives are important scaffolds in medicinal chemistry. Palladium-catalyzed coupling reactions of haloarenes were conducted with diverse five- to seven-membered cyclic β-dicarbonyl derivatives including barbiturate, pyrazolidine-3,5-dione, and 1,4-dia...

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Detalles Bibliográficos
Autores principales: Yun, Jisu, Jeong, Dayeon, Xie, Zhong, Lee, Sol, Kim, Jiho, Surmeier, D. James, Silverman, Richard B., Kang, Soosung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089348/
https://www.ncbi.nlm.nih.gov/pubmed/35559207
http://dx.doi.org/10.1021/acsomega.2c00889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089348/
https://www.ncbi.nlm.nih.gov/pubmed/35559207
http://dx.doi.org/10.1021/acsomega.2c00889

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