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Design, synthesis, and bioactivity evaluation of antitumor sorafenib analogues

Malignant tumors are a serious threat to human health and are generally treated with chemical therapy. This chemical therapy uses agents that act on signal transduction pathway mechanism of tumor with good selectivity and low toxicity. Sorafenib is a multikinase target inhibitor with good tumor inhi...

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Detalles Bibliográficos
Autores principales: Zhou, Shiyang, Chen, Guangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089424/
https://www.ncbi.nlm.nih.gov/pubmed/35558629
http://dx.doi.org/10.1039/c8ra08246d