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Massively-parallel enrichment of minor alleles for mutational testing via low-depth duplex sequencing
The ability to assay large numbers of low-frequency mutations is useful in biomedicine, yet, the technical hurdles of sequencing multiple mutations at extremely high depth, with accuracy, limits their detection in clinical practice. Low-frequency mutations can typically be detected by increasing the...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089460/ https://www.ncbi.nlm.nih.gov/pubmed/35301450 http://dx.doi.org/10.1038/s41551-022-00855-9 |