Heparin-Assisted Amyloidogenesis Uncovered through Molecular Dynamics Simulations

[Image: see text] Glycosaminoglycans (GAGs), in particular, heparan sulfate and heparin, are found colocalized with Aβ amyloid. They have been shown to enhance fibril formation, suggesting a possible pathological connection. We have investigated heparin’s assembly of the KLVFFA peptide fragment usin...

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Detalles Bibliográficos
Autores principales: Khurshid, Beenish, Rehman, Ashfaq Ur, Luo, Ray, Khan, Alamzeb, Wadood, Abdul, Anwar, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089684/
https://www.ncbi.nlm.nih.gov/pubmed/35572757
http://dx.doi.org/10.1021/acsomega.2c01034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089684/
https://www.ncbi.nlm.nih.gov/pubmed/35572757
http://dx.doi.org/10.1021/acsomega.2c01034

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