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Heparin-Assisted Amyloidogenesis Uncovered through Molecular Dynamics Simulations
[Image: see text] Glycosaminoglycans (GAGs), in particular, heparan sulfate and heparin, are found colocalized with Aβ amyloid. They have been shown to enhance fibril formation, suggesting a possible pathological connection. We have investigated heparin’s assembly of the KLVFFA peptide fragment usin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089684/ https://www.ncbi.nlm.nih.gov/pubmed/35572757 http://dx.doi.org/10.1021/acsomega.2c01034 |