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Heterogeneity and clonality of kidney-infiltrating T cells in murine lupus nephritis
We previously found that kidney-infiltrating T cells (KITs) in murine lupus nephritis (LN) resembled dysfunctional T cells that infiltrate tumors. This unexpected finding raised the question of how to reconcile the “exhausted” phenotype of KITs with ongoing tissue destruction in LN. To address this,...
Autores principales: | Smita, Shuchi, Chikina, Maria, Shlomchik, Mark J., Tilstra, Jeremy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089785/ https://www.ncbi.nlm.nih.gov/pubmed/35271505 http://dx.doi.org/10.1172/jci.insight.156048 |
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