Use of antisense oligonucleotides to target Notch3 in skeletal cells

Notch receptors are determinants of cell fate and function, and play an important role in the regulation of bone development and skeletal remodeling. Lateral Meningocele Syndrome (LMS) is a monogenic disorder associated with NOTCH3 pathogenic variants that result in the stabilization of NOTCH3 and a...

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Detalles Bibliográficos
Autores principales: Canalis, Ernesto, Carrer, Michele, Eller, Tabitha, Schilling, Lauren, Yu, Jungeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089911/
https://www.ncbi.nlm.nih.gov/pubmed/35536858
http://dx.doi.org/10.1371/journal.pone.0268225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089911/
https://www.ncbi.nlm.nih.gov/pubmed/35536858
http://dx.doi.org/10.1371/journal.pone.0268225

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