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A convenient one-pot synthesis of N-substituted amidoximes and their application toward 1,2,4-oxadiazol-5-ones

The first direct one-pot approach for the synthesis of N-substituted amidoximes from secondary amides or the intermediate amides has been developed. Through the Ph(3)P–I(2)-mediated dehydrative condensation, a variety of N-aryl and N-alkyl amidoximes (R(1)(C[double bond, length as m-dash]NOH)NHR(2),...

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Detalles Bibliográficos
Autores principales: Phakhodee, Wong, Duangkamol, Chuthamat, Wiriya, Nitaya, Pattarawarapan, Mookda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090163/
https://www.ncbi.nlm.nih.gov/pubmed/35559089
http://dx.doi.org/10.1039/c8ra08207c