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The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis
Identifying predictive biomarkers at early stages of inflammatory arthritis is crucial for starting appropriate therapies to avoid poor outcomes. Monocytes (MOs) and macrophages, largely associated with arthritis, are contributors and sensors of inflammation through epigenetic modifications. In this...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090240/ https://www.ncbi.nlm.nih.gov/pubmed/35324478 http://dx.doi.org/10.1172/jci.insight.158783 |