RhoBTB1 reverses established arterial stiffness in angiotensin II–induced hypertension by promoting actin depolymerization

Arterial stiffness predicts cardiovascular disease and all-cause mortality, but its treatment remains challenging. Mice treated with angiotensin II (Ang II) develop hypertension, arterial stiffness, vascular dysfunction, and a downregulation of Rho-related BTB domain–containing protein 1 (RhoBTB1) i...

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Detalles Bibliográficos
Autores principales: Fang, Shi, Wu, Jing, Reho, John J., Lu, Ko-Ting, Brozoski, Daniel T., Kumar, Gaurav, Werthman, Alec M., Silva, Sebastiao Donato, Muskus Veitia, Patricia C., Wackman, Kelsey K., Mathison, Angela J., Teng, Bi Qing, Lin, Chien-Wei, Quelle, Frederick W., Sigmund, Curt D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090250/
https://www.ncbi.nlm.nih.gov/pubmed/35358093
http://dx.doi.org/10.1172/jci.insight.158043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090250/
https://www.ncbi.nlm.nih.gov/pubmed/35358093
http://dx.doi.org/10.1172/jci.insight.158043

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