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An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model

Greater than 25% of all men develop an inguinal hernia in their lifetime, and more than 20 million inguinal hernia repair surgeries are performed worldwide each year. The mechanisms causing abdominal muscle weakness, the formation of inguinal hernias, or their recurrence are largely unknown. We prev...

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Detalles Bibliográficos
Autores principales: Potluri, Tanvi, Taylor, Matthew J., Stulberg, Jonah J., Lieber, Richard L., Zhao, Hong, Bulun, Serdar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090253/
https://www.ncbi.nlm.nih.gov/pubmed/35439171
http://dx.doi.org/10.1172/jci.insight.152011