Cargando…

An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery

We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify anti-infective compounds that abrogate the pathological consequences in the infected hosts. Here, we demonstrated that a pyridine-3-N-sulfonylpiperidine derivative (4a) protects Drosophila from the acute...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoo, Yeon-Ji, Chung, In-Young, Jalde, Shivakumar S., Choi, Hyun-Kyung, Cho, You-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090290/
https://www.ncbi.nlm.nih.gov/pubmed/35521696
http://dx.doi.org/10.1080/21505594.2022.2069325