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An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery
We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify anti-infective compounds that abrogate the pathological consequences in the infected hosts. Here, we demonstrated that a pyridine-3-N-sulfonylpiperidine derivative (4a) protects Drosophila from the acute...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090290/ https://www.ncbi.nlm.nih.gov/pubmed/35521696 http://dx.doi.org/10.1080/21505594.2022.2069325 |