Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians

BACKGROUND: Master athletes (MAs) prove that preserving a high level of physical function up to very late in life is possible, but the mechanisms responsible for their high function remain unclear. METHODS: We performed muscle biopsies in 15 octogenarian world-class track and field MAs and 14 non-at...

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Detalles Bibliográficos
Autores principales: Ubaida-Mohien, Ceereena, Spendiff, Sally, Lyashkov, Alexey, Moaddel, Ruin, MacMillan, Norah J, Filion, Marie-Eve, Morais, Jose A, Taivassalo, Tanja, Ferrucci, Luigi, Hepple, Russell T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090325/
https://www.ncbi.nlm.nih.gov/pubmed/35404238
http://dx.doi.org/10.7554/eLife.74335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090325/
https://www.ncbi.nlm.nih.gov/pubmed/35404238
http://dx.doi.org/10.7554/eLife.74335

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