Targeting carbonic anhydrase IX and XII isoforms with small molecule inhibitors and monoclonal antibodies

Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins that catalyze a very basic but crucial physiological reaction: the conversion of carbon dioxide into bicarbonate with a release of the proton. CA, especially CAIX and CAXII isoforms gained the attention of many rese...

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Detalles Bibliográficos
Autores principales: Kciuk, Mateusz, Gielecińska, Adrianna, Mujwar, Somdutt, Mojzych, Mariusz, Marciniak, Beata, Drozda, Rafał, Kontek, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090362/
https://www.ncbi.nlm.nih.gov/pubmed/35506234
http://dx.doi.org/10.1080/14756366.2022.2052868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090362/
https://www.ncbi.nlm.nih.gov/pubmed/35506234
http://dx.doi.org/10.1080/14756366.2022.2052868

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