GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases

Colorectal cancer (CRC) remains the third cause of cancer-related mortality in Western countries, metastases are the main cause of death. CRC treatment remains limited by systemic toxicity and chemotherapy resistance. Therefore, nanoparticle-mediated delivery of cytotoxic agents selectively to cance...

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Detalles Bibliográficos
Autores principales: Sala, Rita, Rioja-Blanco, Elisa, Serna, Naroa, Sánchez-García, Laura, Álamo, Patricia, Alba-Castellón, Lorena, Casanova, Isolda, López-Pousa, Antonio, Unzueta, Ugutz, Céspedes, María Virtudes, Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090371/
https://www.ncbi.nlm.nih.gov/pubmed/35532120
http://dx.doi.org/10.1080/10717544.2022.2069302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090371/
https://www.ncbi.nlm.nih.gov/pubmed/35532120
http://dx.doi.org/10.1080/10717544.2022.2069302

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