Mutational spectrum of breast cancer susceptibility genes among women ascertained in a cancer risk clinic in Northeast Brazil

PURPOSE: There is a paucity of data on the spectrum and prevalence of pathogenic variants among women of African ancestry in the Northeast region of Brazil. METHODS: We performed BROCA panel sequencing to identify inherited loss-of-function variants in breast cancer susceptibility genes among 292 Br...

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Detalles Bibliográficos
Autores principales: Felix, Gabriela E. S., Guindalini, Rodrigo Santa Cruz, Zheng, Yonglan, Walsh, Tom, Sveen, Elisabeth, Lopes, Taisa Manuela Machado, Côrtes, Juliana, Zhang, Jing, Carôzo, Polyanna, Santos, Irlânia, Bonfim, Thaís Ferreira, Garicochea, Bernardo, Toralles, Maria Betânia Pereira, Meyer, Roberto, Netto, Eduardo Martins, Abe-Sandes, Kiyoko, King, Mary-Claire, de Oliveira Nascimento, Ivana Lucia, Olopade, Olufunmilayo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090684/
https://www.ncbi.nlm.nih.gov/pubmed/35353237
http://dx.doi.org/10.1007/s10549-022-06560-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090684/
https://www.ncbi.nlm.nih.gov/pubmed/35353237
http://dx.doi.org/10.1007/s10549-022-06560-0

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