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Fullerenemalonates inhibit amyloid beta aggregation, in vitro and in silico evaluation

The onset of Alzheimer's disease (AD) is associated with the presence of neurofibrillary pathology such as amyloid β (Aβ) plaques. Different therapeutic strategies have focused on the inhibition of Aβ aggregate formation; these pathological structures lead to neuronal disorder and cognitive imp...

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Detalles Bibliográficos
Autores principales: Melchor, Martínez-Herrera, Susana, Figueroa-Gerstenmaier, Francisco, García-Sierra, Hiram I., Beltrán, Norma, Rivera-Fernández, Jorge A., Lerma-Romero, Perla Y., López-Camacho, Gustavo, Basurto-Islas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090717/
https://www.ncbi.nlm.nih.gov/pubmed/35558050
http://dx.doi.org/10.1039/c8ra07643j