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Fullerenemalonates inhibit amyloid beta aggregation, in vitro and in silico evaluation
The onset of Alzheimer's disease (AD) is associated with the presence of neurofibrillary pathology such as amyloid β (Aβ) plaques. Different therapeutic strategies have focused on the inhibition of Aβ aggregate formation; these pathological structures lead to neuronal disorder and cognitive imp...
Autores principales: | Melchor, Martínez-Herrera, Susana, Figueroa-Gerstenmaier, Francisco, García-Sierra, Hiram I., Beltrán, Norma, Rivera-Fernández, Jorge A., Lerma-Romero, Perla Y., López-Camacho, Gustavo, Basurto-Islas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090717/ https://www.ncbi.nlm.nih.gov/pubmed/35558050 http://dx.doi.org/10.1039/c8ra07643j |
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