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Vinexin contributes to autophagic decline in brain ageing across species

Autophagic decline is considered a hallmark of ageing. The activity of this intracytoplasmic degradation pathway decreases with age in many tissues and autophagy induction ameliorates ageing in many organisms, including mice. Autophagy is a critical protective pathway in neurons and ageing is the pr...

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Detalles Bibliográficos
Autores principales: Park, So Jung, Frake, Rebecca A., Karabiyik, Cansu, Son, Sung Min, Siddiqi, Farah H., Bento, Carla F., Sterk, Peter, Vicinanza, Mariella, Pavel, Mariana, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090768/
https://www.ncbi.nlm.nih.gov/pubmed/34848853
http://dx.doi.org/10.1038/s41418-021-00903-y