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Cell cycle regulation: p53-p21-RB signaling

The retinoblastoma protein RB and the transcription factor p53 are central tumor suppressors. They are often found inactivated in various tumor types. Both proteins play central roles in regulating the cell division cycle. RB forms complexes with the E2F family of transcription factors and downregul...

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Detalles Bibliográficos
Autor principal: Engeland, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090780/
https://www.ncbi.nlm.nih.gov/pubmed/35361964
http://dx.doi.org/10.1038/s41418-022-00988-z