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Cell cycle regulation: p53-p21-RB signaling
The retinoblastoma protein RB and the transcription factor p53 are central tumor suppressors. They are often found inactivated in various tumor types. Both proteins play central roles in regulating the cell division cycle. RB forms complexes with the E2F family of transcription factors and downregul...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090780/ https://www.ncbi.nlm.nih.gov/pubmed/35361964 http://dx.doi.org/10.1038/s41418-022-00988-z |