1,2,3-Triazole–quinazolin-4(3H)-one conjugates: evolution of ergosterol inhibitor as anticandidal agent

The present study describes the synthesis of 1,2,3-triazole–quinazolinone conjugates (5a–q) from ethyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroquinazoline-2-carboxylate and phenyl azide/substituted phenyl azides employing Cu(i) catalysed Huisgen 1,3-dipolar cycloaddition. The corresponding acids (6a–q) wer...

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Detalles Bibliográficos
Autores principales: Masood, Mir Mohammad, Irfan, Mohammad, Khan, Parvez, Alajmi, Mohamed F., Hussain, Afzal, Garrison, Jered, Rehman, Md. Tabish, Abid, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090800/
https://www.ncbi.nlm.nih.gov/pubmed/35558055
http://dx.doi.org/10.1039/c8ra08426b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090800/
https://www.ncbi.nlm.nih.gov/pubmed/35558055
http://dx.doi.org/10.1039/c8ra08426b

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