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Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression

Olig2 is indispensable for motoneuron and oligodendrocyte fate-specification in the pMN domain of embryonic spinal cords, and also involved in the proliferation and differentiation of several cell types in the nervous system, including neural progenitor cells (NPCs) and oligodendrocytes. However, ho...

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Detalles Bibliográficos
Autores principales: Bizen, Norihisa, Bepari, Asim K., Zhou, Li, Abe, Manabu, Sakimura, Kenji, Ono, Katsuhiko, Takebayashi, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090832/
https://www.ncbi.nlm.nih.gov/pubmed/34974536
http://dx.doi.org/10.1038/s41418-021-00915-8