Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer

Both TP53 and ESR1 mutations occur frequently in estrogen receptor positive (ER+) metastatic breast cancers (MBC) and their distinct roles in breast cancer tumorigenesis and progression are well appreciated. Recent clinical studies discovered mutual exclusivity between TP53 and ESR1 mutations in met...

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Detalles Bibliográficos
Autores principales: Li, Zheqi, Spoelstra, Nicole S., Sikora, Matthew J., Sams, Sharon B., Elias, Anthony, Richer, Jennifer K., Lee, Adrian V., Oesterreich, Steffi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090919/
https://www.ncbi.nlm.nih.gov/pubmed/35538119
http://dx.doi.org/10.1038/s41523-022-00426-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090919/
https://www.ncbi.nlm.nih.gov/pubmed/35538119
http://dx.doi.org/10.1038/s41523-022-00426-w

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