Inhibitory effect of lovastatin on human lung cancer cell proliferation by regulating the ERK1/2 and COX-2 pathways

BACKGROUND: Lovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, effectively inhibiting cholesterol synthesis. Previous research findings showed that lovastatin markedly suppressed tumor cell proliferation and metastasis and induced apoptosis. The present study aimed to determine...

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Detalles Bibliográficos
Autores principales: Liu, Sha, Yang, Ping, Wang, Mingkung, Zhang, Shuang, Wang, Jie, Pan, Tao, Zhou, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091021/
https://www.ncbi.nlm.nih.gov/pubmed/35571660
http://dx.doi.org/10.21037/tcr-22-346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091021/
https://www.ncbi.nlm.nih.gov/pubmed/35571660
http://dx.doi.org/10.21037/tcr-22-346

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