Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2

3C-like protease (3CLpro) processes and liberates functional viral proteins essential for the maturation and infectivity of severe acute respiratory syndrome coronavirus 2, the virus responsible for COVID-19. It has been suggested that 3CLpro is catalytically active as a dimer, making the dimerizati...

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Detalles Bibliográficos
Autores principales: Ferreira, Juliana C., Fadl, Samar, Rabeh, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091064/
https://www.ncbi.nlm.nih.gov/pubmed/35568197
http://dx.doi.org/10.1016/j.jbc.2022.102023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091064/
https://www.ncbi.nlm.nih.gov/pubmed/35568197
http://dx.doi.org/10.1016/j.jbc.2022.102023

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