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Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2
3C-like protease (3CLpro) processes and liberates functional viral proteins essential for the maturation and infectivity of severe acute respiratory syndrome coronavirus 2, the virus responsible for COVID-19. It has been suggested that 3CLpro is catalytically active as a dimer, making the dimerizati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091064/ https://www.ncbi.nlm.nih.gov/pubmed/35568197 http://dx.doi.org/10.1016/j.jbc.2022.102023 |