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Sulforaphane Does Not Protect Right Ventricular Systolic and Diastolic Functions in Nrf2 Knockout Pulmonary Artery Hypertension Mice

PURPOSE: Nrf2 is a nuclear transcription factor and plays an important role in the regulation of oxidative stress and inflammation. We recently demonstrated that sulforaphane (SFN) protected mice from developing pulmonary arterial hypertension (PAH) and right ventricular (RV) dysfunction by elevatin...

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Detalles Bibliográficos
Autores principales: Zhang, Guangyan, Kang, Yin, Cathey, Dakotah, LeBlanc, Amanda J., Cai, Jun, Cai, Lu, Wang, Sheng, Huang, Jiapeng, Keller, Bradley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091145/
https://www.ncbi.nlm.nih.gov/pubmed/35157168
http://dx.doi.org/10.1007/s10557-022-07323-1