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Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a 5-year survival rate of only 11%, due, in part, to late diagnosis, making the need to understand early events in tumorigenesis critical. Acinar-to-ductal metaplasia (ADM), when not resolved, is a PDAC precursor. Recently, we sho...

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Detalles Bibliográficos
Autores principales: Caplan, Leah R., Vavinskaya, Vera, Gelikman, David G., Jyotsana, Nidhi, Trinh, Vincent Q., Olive, Kenneth P., Tan, Marcus C. B., DelGiorno, Kathleen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091171/
https://www.ncbi.nlm.nih.gov/pubmed/35574446
http://dx.doi.org/10.3389/fphys.2022.865452