The Histone Deacetylase Inhibitor I1 Induces Differentiation of Acute Leukemia Cells With MLL Gene Rearrangements via Epigenetic Modification

Acute leukemia (AL) is characterized by excessive proliferation and impaired differentiation of leukemic cells. AL includes acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Previous studies have demonstrated that about 10% of AML and 22% of ALL are mixed lineage leukemia gene rea...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Jingfang, Li, Gentao, Cui, Zihui, Chen, Peilei, Wang, Jinhong, Hu, Zhenbo, Zhang, Lei, Wei, Liuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091196/
https://www.ncbi.nlm.nih.gov/pubmed/35571127
http://dx.doi.org/10.3389/fphar.2022.876076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091196/
https://www.ncbi.nlm.nih.gov/pubmed/35571127
http://dx.doi.org/10.3389/fphar.2022.876076

Ejemplares similares