EZH2 engages TGFβ signaling to promote breast cancer bone metastasis via integrin β1-FAK activation

Bone metastases occur in 50–70% of patients with late-stage breast cancers and effective therapies are needed. The expression of enhancer of zeste homolog 2 (EZH2) is correlated with breast cancer metastasis, but its function in bone metastasis hasn’t been well-explored. Here we report that EZH2 pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lin, Qu, Jingkun, Qi, Yutao, Duan, Yimin, Huang, Yu-Wen, Zhou, Zhifen, Li, Ping, Yao, Jun, Huang, Beibei, Zhang, Shuxing, Yu, Dihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091212/
https://www.ncbi.nlm.nih.gov/pubmed/35538070
http://dx.doi.org/10.1038/s41467-022-30105-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091212/
https://www.ncbi.nlm.nih.gov/pubmed/35538070
http://dx.doi.org/10.1038/s41467-022-30105-0

Ejemplares similares